Shanyan Chen Selected Research

SB 3CT compound

5/2018	Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.
1/2013	Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury.
5/2012	Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.

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Shanyan Chen Research Topics

Disease

4	Brain Ischemia (Cerebral Ischemia) 05/2018 - 05/2012
3	Stroke (Strokes) 10/2019 - 05/2012
2	Cognitive Dysfunction 03/2024 - 01/2022
2	Ischemic Stroke 10/2019 - 05/2018
2	Cerebral Hemorrhage 05/2018 - 01/2014
2	Infarction (Infarctions) 05/2018 - 05/2012
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017 - 01/2015
2	Hemorrhage 01/2017 - 05/2012
2	Brain Injuries (Brain Injury) 01/2017 - 01/2015
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2015 - 01/2013
2	Ischemia 01/2014 - 05/2012
1	Genetic Predisposition to Disease (Genetic Predisposition) 03/2024
1	Infections 08/2020
1	Cerebral Infarction 05/2018
1	Neuroinflammatory Diseases 01/2017
1	Fibrosarcoma 01/2015
1	Necrosis 01/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2013
1	Gliosis 01/2013
1	Embolism (Embolus) 05/2012

Drug/Important Bio-Agent (IBA)

5	GelatinasesIBA 05/2018 - 05/2012
5	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 05/2012
3	SB 3CT compoundIBA 05/2018 - 05/2012
2	Matrix Metalloproteinase InhibitorsIBA 05/2018 - 05/2012
2	Protein Isoforms (Isoforms)IBA 01/2017 - 01/2015
2	cresyl violetIBA 01/2014 - 01/2014
1	Indicators and Reagents (Reagents)IBA 03/2024
1	PhosphopeptidesIBA 03/2024
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	SoilIBA 08/2020
1	ProteomeIBA 10/2019
1	Biomarkers (Surrogate Marker)IBA 10/2019
1	ClusterinIBA 10/2019
1	Blood Proteins (Serum Proteins)IBA 10/2019
1	LipidsIBA 10/2019
1	Oxygen (Dioxygen)IBA 05/2018
1	Tissue Plasminogen Activator (Alteplase)FDA Link 05/2018
1	Amino Acids FDA Link 01/2017
1	N-Methylaspartate (NMDA)IBA 01/2017
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2017
1	Cell-Penetrating PeptidesIBA 01/2017
1	Conditioned Culture MediaIBA 01/2015
1	4-aminophenylmercuriacetateIBA 01/2015
1	SilverIBA 01/2014
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2013
1	Zonula Occludens-1 ProteinIBA 05/2012
1	ethylene sulfide (thiirane)IBA 05/2012
1	LectinsIBA 05/2012
1	Laminin (Merosin)IBA 05/2012

Therapy/Procedure

2	Therapeutics 03/2024 - 05/2012
1	Precision Medicine 03/2024